Mouse

Stressful animal housing conditions and their potential effect on sympathetic neurotransmission in mice

Although the sympathetic nervous system (SNS) plays a major role in mediating the peripheral stress response, due consideration is not usually given to the effects of prolonged stress on the SNS. The present study examined changes in neurotransmission in the...

Year Published: 2002Animal Type: Mouse, Rodent

Citation: D'Arbe, M., Einstein, R., Lavidis, N. A. 2002. Stressful animal housing conditions and their potential effect on sympathetic neurotransmission in mice. American Journal of Physiology 282(5), R1422-1428.

Influences of laboratory environment on behavior

Experimenter identity had the greatest association with tail-withdrawal latency. ... Precisely what differentiated experimenters in the present study remains uncertain. Experimenter age, sex and experience level did not correlate with the observed differences. All experimenters were trained by the principal...

Year Published: 2002Animal Type: Mouse, Rodent

Citation: Chesler, E. J., Wilson, S. G., Lariviere, W. R. et al. 2002. Influences of laboratory environment on behavior. Nature Neuroscience 5, 1101-1102.

Environmental enrichment for rodents and rabbits

Access to a nestlet - which was shredded - and Mouse Igloo probably reduced anxiety and has also helped to decrease mortality in transgenic mice.Placing a Mouse Igloo and a tunnel into the cage of group-housed male mice abolished fighting....

Year Published: 2002Topics: Environmental EnrichmentAnimal Type: Mouse, Rabbit, Rodent

Citation: Biczak, M., Pellecchia, D. 2002. Environmental enrichment for rodents and rabbits. TriBranch Symposium 2002 , unpublished poster presentation.

Developing and testing a novel cage insert, the Mouse House , designed to enrich the lives of laboratory mice without adversely affecting the science

The 'Mouse House' should satisfy requirements for both environmental enrichment and legislation suggesting the use of cage inserts that allow privacy for the animal but facilitate observation. Bar biting was significantly increased [sic] when the 'Mouse House' was provided.

Year Published: 2002Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Key, D., Hewett, A. 2002. Developing and testing a novel cage insert, the Mouse House , designed to enrich the lives of laboratory mice without adversely affecting the science. Animal Technology and Welfare 1, 55-64.

Enrichment slows disease progression in R6/2 Huntington?s disease mice

Housing mice in standard laboratory cages increased the rate of disease progression while housing them in enriched cages slowed the progress to a more 'normal' rate. Mice housed in such deprived conditions are unlikely to prove a good model of...

Year Published: 2002Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Hockly, E., Cordery, P. M., Woodman, B. et al. 2002. Enrichment slows disease progression in R6/2 Huntington?s disease mice. Annals of Neurology 51, 235-242.

Assessing rodent well-being: Report of the 2001 RSPCA/UFAW rodent welfare group meeting

The meetings focused on techniques for assessing pain, suffering and sitress in mice and rats and monitoring the impact of procedures on their welfare.

Year Published: 2002Animal Type: Mouse, Rat, Rodent

Citation: Hawkins, P., Roughan, J., Wilson, A. et al. 2002. Assessing rodent well-being: Report of the 2001 RSPCA/UFAW rodent welfare group meeting. Animal Technology and Welfare 1, 3-12.

Assessing the welfare of genetically modified mice

The present study addresses how the welfare of genetically modified mice can be assessed.

Year Published: 2002Animal Type: Mouse, Rodent

Citation: Francis, R. J. 2002. Assessing the welfare of genetically modified mice. Animal Technology and Welfare 1, 19-21.

Improving housing conditions for laboratory mice: A review of ‘environmental enrichment’

We have reviewed 40 studies carried out between 1987 and 2000, in which preferences as well as the effect of housing modifications have been studied. Mice will work for access to nesting material and make use of this material to...

Year Published: 2002Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Olsson, I. A. S., Dahlborn, K. 2002. Improving housing conditions for laboratory mice: A review of 'environmental enrichment'. Laboratory Animals 36, 243-270.

An enriched environment increases noradrenaline concentration in the mouse brain

After being exposed to an enriched environment for 40 days, noradrenaline content was increased significantly in the parieto-temporo-occipital cortex, the cerebellum and the pons/medulla oblongata. In contrast, no changes were observed in serotonin or dopamine levels in these same regions.

Year Published: 2002Animal Type: Mouse, Rodent

Citation: Naka, F., Shiga, T., Yaguchi, M. et al. 2002. An enriched environment increases noradrenaline concentration in the mouse brain. Brain Research 924, 124-126.

Music, immunity and cancer

The effects of music on the immune system and cancer development were evaluated in rodents subjected to sound stress. Animals were exposed daily to broad band noise around midnight and/or music for 5 hours on the following morning. Thymus and...

Year Published: 2002Animal Type: Mouse, Rat, Rodent

Citation: Nunez, M. J., Mana, P., Linares, D. et al. 2002. Music, immunity and cancer. Life Science 71, 1047-1057.