Mouse

Severity classification of repeated isoflurane anesthesia in C57BL/6JRj mice—Assessing the degree of distress

According to the EU Directive 2010/63, the severity of a procedure has to be classified as mild, moderate or severe. General anesthesia is thought to be mild, but the Directive does not differentiate between single and repeated anesthesia. Therefore, we...

Year Published: 2017Topics: Anesthesia & SedationAnimal Type: Mouse, Rodent

Citation: Hohlbaum, K., Bert, B., Dietze, S. et al. 2017. Severity classification of repeated isoflurane anesthesia in C57BL/6JRj mice—Assessing the degree of distress. PLOS ONE 12(6), e0179588.

Fancy Mice, Fifth Edition

Adult males, on the other hand, must be housed separately, for, if put together, they will fight to the death. As already mentioned, young males of the same litter if never separated from birth may live together for some time,...

Year Published: 1912Animal Type: Mouse, Rodent

Citation: Davies, C. J. 1912. Fancy Mice, Fifth Edition. L Upcott Gill, London, UK.

Effect of cage-induced stereotypies on measures of affective state and recurrent perseveration in CD-1 and C57BL/6 mice

Stereotypies are abnormal repetitive behaviour patterns that are highly prevalent in laboratory mice and are thought to reflect impaired welfare. Thus, they are associated with impaired behavioural inhibition and may also reflect negative affective states. However, in mice the relationship...

Year Published: 2016Topics: Abnormal/Problematic BehaviorAnimal Type: Mouse, Rodent

Citation: Novak, J., Bailoo, J. D., Melotti, L. et al. 2016. Effect of cage-induced stereotypies on measures of affective state and recurrent perseveration in CD-1 and C57BL/6 mice. PLOS ONE 11(5), e0153203.

Factors influencing the toxicity of sympathomimetic amines to solitary mice

A higher susceptibility to ephedrine was noticed in animal exposed to light intensity of 12 ft-c vs. 0.025 ft-c.

Year Published: 1947Animal Type: Mouse, Rodent

Citation: Chance, M. R. A. 1947. Factors influencing the toxicity of sympathomimetic amines to solitary mice. Journal of Pharmacy and Pharmacology 89, 289-296.

Influence of environment on mammary cancer in mice

Animal kept in groups are more resistant to spontaneously developing mammary tumors than animals caged individually.

Year Published: 1944Animal Type: Mouse, Rodent

Citation: Andervont, H. B. 1944. Influence of environment on mammary cancer in mice. Journal of the National Cancer Institute 4, 579-581.

The wall-seeking tendency in three inbred mouse strains (Mus musculus)

Year Published: 1953Animal Type: Mouse, Rodent

Citation: Fredericson, E. 1953. The wall-seeking tendency in three inbred mouse strains (Mus musculus). Journal of Genetic Psychology 82, 143-146.

Whisker-eating mice

In all three cages dominance of one whisker eater over the other could be diagnosed within 24 hours. ... Hairs were eaten but not digested.

Year Published: 1952Animal Type: Mouse, Rodent

Citation: Hauschka, T. S. 1952. Whisker-eating mice. Journal of Heredity 43, 77-80.

Influence of environment on mammary tumors in mice

Group-housed animals are less suceptible to develop mammary tumors than individually housed animals.

Year Published: 1951Animal Type: Mouse, Rodent

Citation: Muhlbock, O. 1951. Influence of environment on mammary tumors in mice. Acta Unio Internationalis Contra Cancrum 7, 351-353.

Effect of strain and group size on the response of mice to sconal anaesthesia

The variance of the response to a barbiturate anaesthetic was greater if male mice were caged either singly or in groups of eight than if they were caged in pairs.

Year Published: 1962Topics: Anesthesia & Sedation, Social Housing & CompanionshipAnimal Type: Mouse, Rodent

Citation: Mackintosh, J. H. 1962. Effect of strain and group size on the response of mice to sconal anaesthesia. Nature 194, 1304.

Strain differences in activity of mice: Influence of illumination

Year Published: 1960Animal Type: Mouse, Rodent

Citation: McClearn, G. E. 1960. Strain differences in activity of mice: Influence of illumination. Journal of Comparative and Physiological Psychology 53, 142-143.