Mouse

Distress analysis of mice with cervical arteriovenous fistulas

The welfare of laboratory animals is a consistent concern for researchers. Its evaluation not only fosters ethical responsibility and addresses legal requirements, but also provides a solid basis for a high quality of research. Recently, a new cervical arteriovenous model...

Year Published: 2021Topics: Disease/Experimental ModelAnimal Type: Mouse, Rodent

Citation: Xie, W., Palme, R., Schafmayer, C. et al. 2021. Distress analysis of mice with cervical arteriovenous fistulas. Animals 11(11), 3051.

Enriched laboratory housing increases sensitivity to social stress in female California mice (Peromyscus californicus)

Domesticated mice and rats have shown to be powerful model systems for biomedical research, but there are cases in which the biology of species is a poor match for the hypotheses under study. The California mouse (Peromyscus californicus) has unique...

Year Published: 2021Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Minie, V. A., Petric, R., Ramos-Maciel, S. et al. 2021. Enriched laboratory housing increases sensitivity to social stress in female California mice (Peromyscus californicus). Applied Animal Behaviour Science 241, 105381.

Infrared thermography in the study of animals’ emotional responses: A critical review

Whether animals have emotions was historically a long-lasting question but, today, nobody disputes that they do. However, how to assess them and how to guarantee animals their welfare have become important research topics in the last 20 years. Infrared thermography...

Year Published: 2021Topics: Emotion, Pain, & Sentience, Welfare AssessmentAnimal Type: Bird, Cat, Cattle, Chicken, Chimpanzee, Dog, Equine, Fowl, Macaque, Marmoset, Mouse, Nonhuman Primate, Other Bird, Pig, Rabbit, Rat, Rodent

Citation: Travain, T., Valsecchi, P. 2021. Infrared thermography in the study of animals' emotional responses: A critical review. Animals 11(9), 2510.

Voluntary oral ingestion of a sedative prior to euthanasia with CO2: Behavioural responses of mice

Laboratory mice are commonly euthanised with carbon dioxide (CO2); however, there is ample evidence that this gas is aversive. Previous work suggests that sedation achieved via injection with benzodiazepines prior to CO2 administration could reduce aversive behaviours during euthanasia. We...

Year Published: 2021Topics: EuthanasiaAnimal Type: Mouse, Rodent

Citation: Rodriguez-Sanchez, R., Barnaby, E., Améndola, L. et al. 2021. Voluntary oral ingestion of a sedative prior to euthanasia with CO2: Behavioural responses of mice. Animals 11(10), 2879.

Roaming in a land of milk and honey: Life trajectories and metabolic rate of female inbred mice living in a semi naturalistic environment

Despite tremendous efforts at standardization, the results of scientific studies can vary greatly, especially when considering animal research. It is important to emphasize that consistent different personality-like traits emerge and accumulate over time in laboratory mice despite genetic and environmental...

Year Published: 2021Topics: HousingAnimal Type: Mouse, Rodent

Citation: Mieske, P., Diederich, K., Lewejohann, L. 2021. Roaming in a land of milk and honey: Life trajectories and metabolic rate of female inbred mice living in a semi naturalistic environment. Animals 11(10), 3002.

Refining procedures within regulatory toxicology studies: Improving animal welfare and data

During the development of potential new medicines or agrochemicals, an assessment of the safety profile to humans and environmental species is conducted using a range of different in silico and in vitro techniques in conjunction with metabolism and toxicity studies...

Year Published: 2021Topics: Biological Sampling & Physiological Measurement, Cannulation, Catheterization, & Intubation, HousingAnimal Type: Dog, Fish, Mouse, Nonhuman Primate, Pig, Rabbit, Rat, Rodent

Citation: Prior, H., Blunt, H., Crossman, L. et al. 2021. Refining procedures within regulatory toxicology studies: Improving animal welfare and data. Animals 11(11), 3057.

Refinements in head plate mouse nesting: Using composite nests to enhance welfare

When given the opportunity, mice will choose to build nests using multiple different materials. Studies indicate that providing mice with choices which mimic the natural environment allows laboratory mice to build the best quality nests and mice have also been...

Year Published: 2021Topics: Environmental Enrichment, External Bodily EquipmentAnimal Type: Mouse, Rodent

Citation: Windsor, Z. 2021. Refinements in head plate mouse nesting: Using composite nests to enhance welfare. Animal Technology and Welfare 20(2), 135-141.

Thinking outside of the tunnel for non-aversive mouse handling

The key to non-aversive methods of handling lies in understanding what capture method creates the least anxiety in mice: be this tunnel or cupping or another method. It is important that we do not get so focussed on tunnel handling,...

Year Published: 2021Topics: HandlingAnimal Type: Mouse, Rodent

Citation: Moore, J., Wickert, M. 2021. Thinking outside of the tunnel for non-aversive mouse handling. Animal Technology and Welfare 20(2), 161-163.

A tunnel is not enough: Mice benefit from in-cage provision of a communal shelter as well as a handling tunnel

Mouse shelters can provide mice with security, help them thermoregulate, offer darkness to prevent damage to their eyes and enable climbing and gnawing opportunities. For laboratory mice, there is a vast array of commercially available cage furniture, so choosing which...

Year Published: 2021Topics: Environmental Enrichment, HousingAnimal Type: Mouse, Rodent

Citation: Burn, C. C., Popat, R. 2021. A tunnel is not enough: Mice benefit from in-cage provision of a communal shelter as well as a handling tunnel. Animal Technology and Welfare 20(3), 203-210.

Maximising efficacy of your health monitoring programme

There are a multitude of health monitoring techniques/ methods available. It can be difficult to know which of these to use and when to use them. This is an attempt to simplify, maximise the efficacy of and ultimately reduce the...

Year Published: 2021Topics: Husbandry & ManagementAnimal Type: Chinchilla, Gerbil, Guinea Pig, Hamster, Mouse, Rat, Rodent

Citation: Dickinson, A. 2021. Maximising efficacy of your health monitoring programme. Animal Technology and Welfare 20(3), 255-257.