Macaque

Five hot topics in refinement of nonhuman primate neuroscience research

Members of the North American 3Rs Collaborative (NA3RsC) refinement initiative have chosen to summarize developments in five hot topics of interest: 1. Tips for welfare-friendly transport, chairing, and restraint; 2. Guidance on refining food and fluid control; 3. Protective caps...

Year Published: 2022Topics: Cannulation, Catheterization, & Intubation, Handling, Husbandry & Management, Imaging & Electrophysiological Recording, Relocation & Transport, RestraintAnimal Type: Macaque, Marmoset, Nonhuman Primate

Citation: Buckmaster, C. L., Levesque, D., LaFollette, M. et al. 2022. Five hot topics in refinement of nonhuman primate neuroscience research. Laboratory Animal Science Professional 10(1) (January/February), 24-26.

Creative enrichment for nonhuman primates

Providing novel and creative enrichments for nonhuman primates improves their mental wellbeing and is thus an important aspect of all husbandry programs. These enrichments are often presented through variations in diet, toys, and environmental features. The challenge with any type...

Year Published: 2022Topics: Environmental EnrichmentAnimal Type: Baboon, Capuchin, Chimpanzee, Lemur, Macaque, Marmoset, Nonhuman Primate, Other Nonhuman Primate, Owl Monkey, Squirrel Monkey, Vervet (African Green Monkey)

Citation: Medina, A. 2022. Creative enrichment for nonhuman primates. Laboratory Animal Science Professional 10(1) (January/February), 42-43.

DIY: Ants on a log

This traditional snack has a variety of options for NHP enrichment. From fruit to cereals, get creative with the “ants” and remember to consider different fillings for the celery log.

Citation: Buchanan, K. 2022. DIY: Ants on a log. Laboratory Animal Science Professional 10(1) (January/February), 44.

Development and implementation of a positive reinforcement training program for nonhuman primates in biomedical research

Despite clear benefits of PRT for NHPs and biomedical research, investigators often view the investment in personnel expertise and time required to train animals as deterrents towards adopting PRT. We provide an example of how this framework could be implemented...

Year Published: 2022Topics: Animal Training, Drug/Substance AdministrationAnimal Type: Macaque, Nonhuman Primate

Citation: Guerrero-Martin, S. M., Brill, S., Carlson, B. W. 2022. Development and implementation of a positive reinforcement training program for nonhuman primates in biomedical research. Laboratory Animal Science Professional 10(1) (January/February), 48-52.

Chronic collection of cerebrospinal fluid from rhesus macaques (Macaca mulatta) with cisterna magna ports: Update on refinements

More than 20 y ago, we developed an animal model for chronic and continuous collection of cerebrospinal fluid (CSF) from conscious rhesus macaques. Since our previous publication in 2003, we have successfully implanted 168 rhesus macaques using this approach. Our...

Year Published: 2022Topics: Biological Sampling & Physiological MeasurementAnimal Type: Macaque, Nonhuman Primate

Citation: Gilberto, D., Michener, M., Smith, B. et al. 2022. Chronic collection of cerebrospinal fluid from rhesus macaques (Macaca mulatta) with cisterna magna ports: Update on refinements. Comparative Medicine 72(1), 45-49.

Sex differences in hierarchical stability in a formation of a mixed-sex group of rhesus macaques

Forming groups of captive rhesus macaques (Macaca mulatta) is a common management practice. New formations of unfamiliar macaques can be costly, with high levels of trauma, particularly as intense aggression is used to establish a dominance hierarchy. Combining previous subgroups...

Year Published: 2022Topics: Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Wooddell, L. J., Beisner, B. A., Nathman, A. C. et al. 2022. Sex differences in hierarchical stability in a formation of a mixed-sex group of rhesus macaques. JAALAS 61(1), 67-74.

Bedding as an enrichment strategy in group-housed Mauritian cynomolgus macaques (Macaca fascicularis)

The research community is committed to improving the well-being of nonhuman primates by providing opportunities to express species-specific behaviors such as foraging. In the wild, macaques spend a large part of their day foraging; this behavior is greatly limited in...

Year Published: 2022Topics: Environmental Enrichment, Husbandry & ManagementAnimal Type: Macaque, Nonhuman Primate

Citation: Janavaris, M., Bader, L., Hansen, J. J. et al. 2022. Bedding as an enrichment strategy in group-housed Mauritian cynomolgus macaques (Macaca fascicularis). JAALAS 61(2), 159-164.

Influence of pair-housing on sleep parameters evaluated with actigraphy in female rhesus monkeys

Rhesus monkeys are naturally social animals, and behavioral management strategies have focused on promoting pairhousing in laboratory settings as an alternative to individual or group housing. In humans, co-sleeping can have a major impact on bed partners' sleep, raising the...

Year Published: 2022Topics: Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Berro, L. F., Pareek, T., Reeves-Darby, J. A. et al. 2022. Influence of pair-housing on sleep parameters evaluated with actigraphy in female rhesus monkeys. JAALAS 61(2), 165-172.

Single-dose diazepam administration improves pairing success of unfamiliar adult male rhesus macaques (Macaca mulatta)

Social housing is one of the best forms of environmental enhancement for nonhuman primates, and current research into pair compatibility and introduction techniques focuses on improving safety and outcome. The gradual steps method (GS), which is widely used for introducing...

Year Published: 2022Topics: Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Kezar, S. M., Baker, K. C., Russell-Lodrigue, K. E. et al. 2022. Single-dose diazepam administration improves pairing success of unfamiliar adult male rhesus macaques (Macaca mulatta). JAALAS 61(2), 173-180.

Chronic captivity stress in wild animals is highly species-specific

Wild animals are brought into captivity for many reasons—conservation, research, agriculture and the exotic pet trade. While the physical needs of animals are met in captivity, the conditions of confinement and exposure to humans can result in physiological stress. The...

Year Published: 2019Topics: HousingAnimal Type: All/General, Amphibian, Baboon, Capuchin, Chimpanzee, Crocodile & Alligator, Frog & Toad, Gibbon, Lemur, Lizard, Macaque, Marine Mammal, Marmoset, Nonhuman Primate, Other Animal, Other Nonhuman Primate, Owl Monkey, Reptile, Salamander, Snake, Squirrel Monkey, Turtle & Tortoise, Vervet (African Green Monkey)

Citation: Fischer, C. P., Romero, L. M. 2019. Chronic captivity stress in wild animals is highly species-specific. Conservation Physiology 7(1), coz093.