Macaque

Recommendations for measuring and standardizing light for laboratory mammals to improve welfare and reproducibility in animal research

Light enables vision and exerts widespread effects on physiology and behavior, including regulating circadian rhythms, sleep, hormone synthesis, affective state, and cognitive processes. Appropriate lighting in animal facilities may support welfare and ensure that animals enter experiments in an appropriate...

Year Published: 2024Topics: Husbandry & ManagementAnimal Type: All/General, Cat, Dog, Goat, Macaque, Marmoset, Mouse, Nonhuman Primate, Pig, Rat, Rodent, Sheep, Vervet (African Green Monkey)

Citation: Lucas, R. J., Allen, A. E., Brainard, G. C. et al. 2024. Recommendations for measuring and standardizing light for laboratory mammals to improve welfare and reproducibility in animal research. PLOS Biology 22(3), e3002535.

Development of a novel primate welfare assessment tool for research macaques

Primates are important species for biomedical research and ensuring their good welfare is critical for research translatability and ethical responsibility. Systematic animal welfare assessments can support continuous programme improvements and build institutional awareness of areas requiring more attention. A multi-facility,...

Year Published: 2024Topics: Welfare AssessmentAnimal Type: Macaque, Nonhuman Primate

Citation: Paterson, E. A., O'Malley, C. I., Abney, D. M. et al. 2024. Development of a novel primate welfare assessment tool for research macaques. Animal Welfare 33, e3.

Development of an animal welfare tool for zoo-housed primates, considering intra- and inter-rater reliability

Over the past few decades, the concept of animal welfare has become increasingly prominent in Western societies. Faced with this collective awareness, various organisations are now making it a point of honour to consider the welfare of their animals. This...

Year Published: 2024Topics: Welfare AssessmentAnimal Type: Baboon, Capuchin, Chimpanzee, Lemur, Macaque, Marmoset, Nonhuman Primate, Other Nonhuman Primate, Owl Monkey, Squirrel Monkey, Vervet (African Green Monkey)

Citation: Dazord, A., Primault, M. 2024. Development of an animal welfare tool for zoo-housed primates, considering intra- and inter-rater reliability. Journal of Zoo and Aquarium Research 12(2), 69–78.

Social stability via management of natal males in captive rhesus macaques (Macaca mulatta)

Keystone individuals are expected to disproportionately contribute to group stability. For instance, rhesus macaques (Macaca mulatta) who police conflict contribute towards stability. Not all individuals' motivations align with mechanisms of group stability. In wild systems, males typically disperse at maturity...

Year Published: 2024Topics: Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Pritchard, A. J., Beisner, B. A., Nathman, A. et al. 2024. Social stability via management of natal males in captive rhesus macaques (Macaca mulatta). Journal of Applied Animal Welfare Science 27(2), 408–425.

Sleep quality in cynomolgus macaques (Macaca fascicularis) varies by housing type and following surgery

Sleep is an important contributor to good physical and mental health and an important component of post-surgical recovery. The assessment of dark phase (‘nighttime') behavior can provide insight into the efficacy of analgesic treatments and should be considered when assessing...

Year Published: 2024Topics: Housing, Social Housing & Companionship, Surgery & Post-OpAnimal Type: Macaque, Nonhuman Primate

Citation: Paterson, E. A., O'Malley, C. I., Turner, P. V. 2024. Sleep quality in cynomolgus macaques (Macaca fascicularis) varies by housing type and following surgery. Applied Animal Behaviour Science 272, 106188.

Benchmarking enrichment efforts in the US & Canada across species and enrichment categories

Enrichment is important for animal welfare and data quality. Provision of enrichment opportunities varies between species and enrichment category. However, data benchmarking these differences does not exist. Our objective was to characterize enrichment provision and associated factors across species in...

Year Published: 2023Topics: Environmental EnrichmentAnimal Type: Cat, Cattle, Chicken, Dog, Ferret, Goat, Macaque, Mink, Mouse, Nonhuman Primate, Rabbit, Rat, Rodent, Sheep

Citation: LaFollette, M. R., Cloutier, S., Brady, C. M. et al. 2023. Benchmarking enrichment efforts in the US & Canada across species and enrichment categories. JAALAS 62(4), 303–316.

Modular, cement-free, customized headpost and connector-chamber implants for macaques

Background: Neurophysiological studies with awake macaques typically require chronic cranial implants. Headpost and connector-chamber implants are used to allow head stabilization and to house connectors of chronically implanted electrodes, respectively. New method: We present long-lasting, modular, cement-free headpost implants made...

Year Published: 2023Topics: External Bodily EquipmentAnimal Type: Macaque, Nonhuman Primate

Citation: Psarou, E., Vezoli, J., Schölvinck, M. L. et al. 2023. Modular, cement-free, customized headpost and connector-chamber implants for macaques. Journal of Neuroscience Methods 393, 109899.

The impact of housing on birth outcomes in breeding macaque groups across multiple research centers

Demand for nonhuman primates in research has increased over the past several years, while nonhuman primate supply remains a challenge in the United States. Global nonhuman primate supply issues make it increasingly important to maximize domestic colony production. To explore...

Year Published: 2023Topics: Housing, Rearing & WeaningAnimal Type: Macaque, Nonhuman Primate

Citation: Haertel, A. J., Beisner, B. A., Buehler, M. S. et al. 2023. The impact of housing on birth outcomes in breeding macaque groups across multiple research centers. American Journal of Primatology 85(11), e23554.

Less invasive, simultaneous, and continuous measurements of locomotor activity and body temperature using the nano tag® small accelerometer device in cynomolgus monkeys

Locomotor activity and body temperature evaluations of cynomolgus monkeys are useful to understand the effects of drugs on the central nervous system. Here, we describe a simple, inexpensive, and less invasive evaluation method using the nano tag® (KISSEI COMTEC Co.,...

Year Published: 2022Topics: Biological Sampling & Physiological MeasurementAnimal Type: Macaque, Nonhuman Primate

Citation: Kishida, T., Motokawa, Y., Yokoi, R. et al. 2022. Less invasive, simultaneous, and continuous measurements of locomotor activity and body temperature using the nano tag® small accelerometer device in cynomolgus monkeys. Journal of Pharmacological and Toxicological Methods 118, 107224.

Blood microsampling in cynomolgus monkey and evaluation of plasma PK parameters in comparison to conventional sampling

Microsampling, a reduced volume sampling method, has successfully gained attention at the International Conference on Harmonization (ICH) level and established benefits support its use in Toxicokinetic (TK) studies. These improved sampling techniques are less invasive and in large animal species...

Year Published: 2023Topics: Biological Sampling & Physiological MeasurementAnimal Type: Macaque, Nonhuman Primate

Citation: Bertani, S., Donadi, A., Franchi, J. et al. 2023. Blood microsampling in cynomolgus monkey and evaluation of plasma PK parameters in comparison to conventional sampling. Journal of Pharmacological and Toxicological Methods 123, 107298.