Macaque

Daily water intake by common marmosets (Callithrix jacchus) and recommendations regarding fluid regulation

The typical daily water intake of common marmosets (Callithrix jacchus) in a research setting has not been well characterized. Because these New World primates are in demand as animal models for neurobehavioral experiments, which can include the potential use of...

Year Published: 2019Topics: Husbandry & Management, Natural BehaviorAnimal Type: Macaque, Nonhuman Primate

Citation: Winn, C. B., Issa, E. B., Curcillo, C. P. et al. 2019. Daily water intake by common marmosets (Callithrix jacchus) and recommendations regarding fluid regulation. JAALAS 58(1), 16-20.

Regional anesthesia for dentistry and orofacial surgery in rhesus macaques (Macaca mulatta)

Regional anesthesia is a commonly used adjunct to orofacial dental and surgical procedures in companion animals and humans. However, appropriate techniques for anesthetizing branches of the mandibular and maxillary nerves have not been described for rhesus monkeys. Skulls of 3...

Year Published: 2019Topics: Anesthesia & Sedation, Disease/Experimental ModelAnimal Type: Macaque, Nonhuman Primate

Citation: Engel, R. M., Thomas III, M. L., Banks, R. E. 2019. Regional anesthesia for dentistry and orofacial surgery in rhesus macaques (Macaca mulatta). JAALAS 58(2), 223-230.

Interest in non-social novel stimuli as a function of age in rhesus monkeys

Human cognitive and affective life changes with healthy ageing; cognitive capacity declines while emotional life becomes more positive and social relationships are prioritized. This may reflect an awareness of limited lifetime unique to humans, leading to a greater interest in...

Year Published: 2019Topics: Environmental EnrichmentAnimal Type: Macaque, Nonhuman Primate

Citation: Bliss-Moreau, E., Baxter, M. G. 2019. Interest in non-social novel stimuli as a function of age in rhesus monkeys. Royal Society Open Science 6(9), 182237.

Minimally invasive lumbar port system for the collection of cerebrospinal fluid from rhesus macaques (Macaca mulatta)

Biomedical translational research frequently incorporates collection of CSF from NHP, because CSF drug levels are used as a surrogate for CNS tissue penetration in pharmacokinetic and dynamic studies. Surgical placement of a CNS ventricular catheter reservoir for CSF collection is...

Year Published: 2016Topics: Biological Sampling & Physiological MeasurementAnimal Type: Macaque, Nonhuman Primate

Citation: MacAllister, R. P., Lester McCully, C. M., Bacher, J. et al. 2016. Minimally invasive lumbar port system for the collection of cerebrospinal fluid from rhesus macaques (Macaca mulatta). Comparative Medicine 66(4), 349–352.

An international survey of approaches to chair restraint of nonhuman primates

Specifically designed restraint chairs are the preferred method of restraint for research studies that require NHP to sit in place for sustained periods of time. In light of increasing emphasis on refinement of restraint to improve animal wellbeing, it is...

Year Published: 2017Topics: RestraintAnimal Type: Baboon, Capuchin, Chimpanzee, Lemur, Macaque, Marmoset, Nonhuman Primate, Other Nonhuman Primate, Owl Monkey, Squirrel Monkey, Vervet (African Green Monkey)

Citation: McMillan, J. L., Bloomsmith, M. A., Prescott, M. J. 2017. An international survey of approaches to chair restraint of nonhuman primates. Comparative Medicine 67(5), 442–451.

Hypercortisolemia and depressive-like behaviors in a rhesus macaque (Macaca mulatta) involved in visual research

A 10-y-old cranially implanted rhesus macaque (Macaca mulatta) involved in visual research was presented for dull mentation and weight loss. Physical examination revealed alopecia and poor body conditioning, and bloodwork revealed marked hypercortisolemia (23 μg/dL). Differential diagnoses for hypercortisolemia, weight...

Year Published: 2017Topics: Emotion, Pain, & Sentience, Environmental EnrichmentAnimal Type: Macaque, Nonhuman Primate

Citation: Adams, S. C., Guyot, C. M., Berry, K. M. et al. 2017. Hypercortisolemia and depressive-like behaviors in a rhesus macaque (Macaca mulatta) involved in visual research. Comparative Medicine 67(6), 529–536.

Retrospective review of surgical outcomes and pair-housing success in vasectomized rhesus macaques (Macaca mulatta)

Providing social housing for adult male macaques can be challenging. One successful strategy for long-term social housing of adult male macaques is to pair them with adult females; however, unwanted breeding must be prevented by sterilization of the male or...

Year Published: 2018Topics: Reproduction, Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Ekanayake-Alper,D. K., Wilson, S. R., Scholz, J. A. 2018. Retrospective review of surgical outcomes and pair-housing success in vasectomized rhesus macaques (Macaca mulatta). Comparative Medicine 68(2), 168–176.

Social management of laboratory rhesus macaques housed in large groups using a network approach: A review

Biomedical facilities across the nation and worldwide aim to develop cost-effective methods for the reproductive management of macaque breeding groups, typically by housing macaques in large, multi-male multi-female social groups that provide monkey subjects for research as well as appropriate...

Year Published: 2018Topics: Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: McCowan, B., Beisner, B., Hannibal, D. 2018. Social management of laboratory rhesus macaques housed in large groups using a network approach: A review. Behavioural Processes 156, 77-82.

Systematic assessment of food item preference and reinforcer effectiveness: Enhancements in training laboratory-housed rhesus macaques

The use of systematic preference assessments can enhance positive reinforcement training with captive animals. We found that the multiple stimulus without replacement (MSWO) technique identified food preferences in laboratory housed rhesus macaques, with raisins and grapes being ranked higher on...

Year Published: 2018Topics: Animal TrainingAnimal Type: Macaque, Nonhuman Primate

Citation: Martin, A. L., Franklin, A. N., Perlman, J. E. et al. 2018. Systematic assessment of food item preference and reinforcer effectiveness: Enhancements in training laboratory-housed rhesus macaques. Behavioural Processes 157, 445-452.

Preliminary validation of natural depression in macaques with acute treatments of the fast-acting antidepressant ketamine

Non-human primates have become one of the most important model animals for the investigation of brain diseases because they share a wide-range of genetics and social similarities with human beings. Naturally-evoked depression models in macaques may offer a full spectrum...

Year Published: 2019Topics: Emotion, Pain, & SentienceAnimal Type: Macaque, Nonhuman Primate

Citation: Chu, X. 2019. Preliminary validation of natural depression in macaques with acute treatments of the fast-acting antidepressant ketamine. Behavioural Brain Research 360, 60-68.