Macaque

Confirming sexual maturity in male cynomolgus macaques by urinary spermatozoa microscopic examination

Medications often require studies performed in sexually mature cynomolgus macaques. At this time, there are few options available to confirm sexual maturity in male macaques. Electroejaculation and collection of seminal fluid are invasive and require either anesthesia or prolonged acclimation....

Year Published: 2022Topics: ReproductionAnimal Type: Macaque, Nonhuman Primate

Citation: Rosales, C., Sands, C. 2022. Confirming sexual maturity in male cynomolgus macaques by urinary spermatozoa microscopic examination. Laboratory Animal Science Professional 10(1) (January/February), 60-61.

Interpreting macaque facial expressions and body behavior in preparation for social housing

This article will help those who are new to working with non-human primates. Interpreting macaque facial expressions and body behavior is important for beginning the process of pair housing two animals.

Year Published: 2022Topics: Natural Behavior, Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Tomeczko, S. 2022. Interpreting macaque facial expressions and body behavior in preparation for social housing. Laboratory Animal Science Professional 10(1) (January/February), 62-63.

Considering sustenance preference to motivate and enhance NHP learning and performance

Finding and utilizing the specific taste preferences of the rhesus macaque in the laboratory setting can be a valuable step towards promoting cooperative, positively reinforced training. It can also be a wonderful tool for enrichment by allowing the subject to...

Year Published: 2022Topics: Animal Training, Environmental EnrichmentAnimal Type: Macaque, Nonhuman Primate

Citation: Gregoire, A. 2022. Considering sustenance preference to motivate and enhance NHP learning and performance. Laboratory Animal Science Professional 10(1) (January/February), 12-14.

Enhancing animal welfare by providing custom caging space for nonhuman primates

The YNPRC recently renovated two NHP housing areas with a novel facility design and equipped with a customized caging system that offers additional outdoor access, socialization, and enrichment opportunities for NHPs assigned to infectious disease studies, awaiting biomedical research assignment,...

Year Published: 2022Topics: Environmental Enrichment, Housing, Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Stammen, R. L., Cohen, J. K., Connor-Stroud, F. R. et al. 2022. Enhancing animal welfare by providing custom caging space for nonhuman primates. Laboratory Animal Science Professional 10(1) (January/February), 20-23.

Five hot topics in refinement of nonhuman primate neuroscience research

Members of the North American 3Rs Collaborative (NA3RsC) refinement initiative have chosen to summarize developments in five hot topics of interest: 1. Tips for welfare-friendly transport, chairing, and restraint; 2. Guidance on refining food and fluid control; 3. Protective caps...

Year Published: 2022Topics: Cannulation, Catheterization, & Intubation, Handling, Husbandry & Management, Imaging & Electrophysiological Recording, Relocation & Transport, RestraintAnimal Type: Macaque, Marmoset, Nonhuman Primate

Citation: Buckmaster, C. L., Levesque, D., LaFollette, M. et al. 2022. Five hot topics in refinement of nonhuman primate neuroscience research. Laboratory Animal Science Professional 10(1) (January/February), 24-26.

Creative enrichment for nonhuman primates

Providing novel and creative enrichments for nonhuman primates improves their mental wellbeing and is thus an important aspect of all husbandry programs. These enrichments are often presented through variations in diet, toys, and environmental features. The challenge with any type...

Year Published: 2022Topics: Environmental EnrichmentAnimal Type: Baboon, Capuchin, Chimpanzee, Lemur, Macaque, Marmoset, Nonhuman Primate, Other Nonhuman Primate, Owl Monkey, Squirrel Monkey, Vervet (African Green Monkey)

Citation: Medina, A. 2022. Creative enrichment for nonhuman primates. Laboratory Animal Science Professional 10(1) (January/February), 42-43.

DIY: Ants on a log

This traditional snack has a variety of options for NHP enrichment. From fruit to cereals, get creative with the “ants” and remember to consider different fillings for the celery log.

Citation: Buchanan, K. 2022. DIY: Ants on a log. Laboratory Animal Science Professional 10(1) (January/February), 44.

Development and implementation of a positive reinforcement training program for nonhuman primates in biomedical research

Despite clear benefits of PRT for NHPs and biomedical research, investigators often view the investment in personnel expertise and time required to train animals as deterrents towards adopting PRT. We provide an example of how this framework could be implemented...

Year Published: 2022Topics: Animal Training, Drug/Substance AdministrationAnimal Type: Macaque, Nonhuman Primate

Citation: Guerrero-Martin, S. M., Brill, S., Carlson, B. W. 2022. Development and implementation of a positive reinforcement training program for nonhuman primates in biomedical research. Laboratory Animal Science Professional 10(1) (January/February), 48-52.

Chronic collection of cerebrospinal fluid from rhesus macaques (Macaca mulatta) with cisterna magna ports: Update on refinements

More than 20 y ago, we developed an animal model for chronic and continuous collection of cerebrospinal fluid (CSF) from conscious rhesus macaques. Since our previous publication in 2003, we have successfully implanted 168 rhesus macaques using this approach. Our...

Year Published: 2022Topics: Biological Sampling & Physiological MeasurementAnimal Type: Macaque, Nonhuman Primate

Citation: Gilberto, D., Michener, M., Smith, B. et al. 2022. Chronic collection of cerebrospinal fluid from rhesus macaques (Macaca mulatta) with cisterna magna ports: Update on refinements. Comparative Medicine 72(1), 45-49.

Sex differences in hierarchical stability in a formation of a mixed-sex group of rhesus macaques

Forming groups of captive rhesus macaques (Macaca mulatta) is a common management practice. New formations of unfamiliar macaques can be costly, with high levels of trauma, particularly as intense aggression is used to establish a dominance hierarchy. Combining previous subgroups...

Year Published: 2022Topics: Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Wooddell, L. J., Beisner, B. A., Nathman, A. C. et al. 2022. Sex differences in hierarchical stability in a formation of a mixed-sex group of rhesus macaques. JAALAS 61(1), 67-74.