All/General

Why all healthy laboratory animals should be rehomed, no matter how small

This paper explores the ethical imperative of rehoming all healthy animals of sentient species after experiments have finished or when they have become otherwise redundant. We take into account disparate perspectives in animal ethics and see how they point in...

Year Published: 2023Topics: Regulations & Ethical ReviewAnimal Type: All/General, Mouse, Rat, Rodent

Citation: Van Loo, P. L. P., Janssens, M. R. E. 2023. Why all healthy laboratory animals should be rehomed, no matter how small. Animals 13(17), 2727.

As the world turns: Identifying and documenting continuing education for IACUC committee members and staff

In this column, we will describe how the IACUC Office at the University of Texas Southwestern Medical Center (UTSW) identifies and documents the participation of IACUC members and staff in continuing education opportunities. The prioritization of continuing education (CE) in...

Year Published: 2022Topics: Regulations & Ethical ReviewAnimal Type: All/General

Citation: Wilkerson, J., Cavanaugh, K. 2022. As the world turns: Identifying and documenting continuing education for IACUC committee members and staff. Laboratory Animal Science Professional 10(6) (November/December), 36-38.

Unmasking the adverse impacts of sex bias on science and research animal welfare

Sex bias in biomedical and natural science research has been prevalent for decades. In many cases, the female estrous cycle was thought to be too complex an issue to model for, and it was thought to be simpler to only...

Year Published: 2023Topics: Regulations & Ethical ReviewAnimal Type: All/General

Citation: Nunamaker, E. A., Turner, P. V. 2023. Unmasking the adverse impacts of sex bias on science and research animal welfare. Animals 13(17), 2792.

Knowledge of lateralized brain function can contribute to animal welfare

The specialized functions of each hemisphere of the vertebrate brain are summarized together with the current evidence of lateralized behavior in farm and companion animals, as shown by the eye or ear used to attend and respond to stimuli. Forelimb...

Year Published: 2023Topics: Personality, Welfare AssessmentAnimal Type: All/General

Citation: Rogers, L. J. 2023. Knowledge of lateralized brain function can contribute to animal welfare. Frontiers in Veterinary Science 10.

The agency domain and behavioral interactions: Assessing positive animal welfare using the Five Domains Model

Year Published: 2023Topics: Welfare AssessmentAnimal Type: All/General, Dog, Other Animal

Citation: Littlewood, K. E., Heslop, M. V., Cobb, M. L. 2023. The agency domain and behavioral interactions: Assessing positive animal welfare using the Five Domains Model. Frontiers in Veterinary Science 10.

Non-invasive assessment of the intraventricular pressure using novel color M-mode echocardiography in animal studies: Current status and future perspectives in veterinary medicine

The assessment of diastolic function has received great interest in order to comprehend its crucial role in the pathophysiology of heart failure and for the early identification of cardiac events. Silent changes in the intraventricular flow (IVF) dynamics occur before...

Year Published: 2023Topics: Biological Sampling & Physiological Measurement, Cannulation, Catheterization, & IntubationAnimal Type: All/General

Citation: Mandour, A. S., Farag, A., Helal, M. A. Y. et al. 2023. Non-invasive assessment of the intraventricular pressure using novel color M-mode echocardiography in animal studies: Current status and future perspectives in veterinary medicine. Animals 13(15), 2452.

European Union legislation for the welfare of animals used for scientific purposes: Areas identified for further discussion

The Directive 2010/63/EU of the European Parliament and of the Council has been in force for more than a decade and has brought about significant improvements and novel requirements for the welfare of animals used for scientific purposes, while safeguarding...

Year Published: 2023Topics: Regulations & Ethical ReviewAnimal Type: All/General

Citation: Marinou, K. A., Dontas, I. A. 2023. European Union legislation for the welfare of animals used for scientific purposes: Areas identified for further discussion. Animals 13(14), 2367.

The 3Rs in experimental liver disease

Patients with cirrhosis present multiple physiological and immunological alterations that play a very important role in the development of clinically relevant secondary complications to the disease. Experimentation in animal models is essential to understand the pathogenesis of human diseases and,...

Year Published: 2023Topics: Disease/Experimental ModelAnimal Type: All/General, Mouse, Rat, Rodent

Citation: Martinez-Lopez, S., Angel-Gomis, E., Sanchez-Ardid, E. et al. 2023. The 3Rs in experimental liver disease. Animals 13(14), 2357.

Choice, control, and animal welfare: Definitions and essential inquiries to advance animal welfare science

The ways in which humans can support good welfare for animals in their care is an ongoing subject of debate: some place emphasis on the animals' physical health; others, on animals' ability to live “natural lives”; and others on animals'...

Year Published: 2023Topics: Environmental Enrichment, Natural BehaviorAnimal Type: All/General, Macaque, Nonhuman Primate

Citation: Englund, M. D., Cronin, K. A. 2023. Choice, control, and animal welfare: Definitions and essential inquiries to advance animal welfare science. Frontiers in Veterinary Science 10.

CIRS-LAS – a novel approach to increase transparency in laboratory animal science for improving animal welfare by reducing laboratory animal distress

The 3Rs principle is highly topical in animal-based research. These include, above all, new scientific methods for conducting experiments without an animal model, by using non-animal models (Replace), reducing the number of laboratory animals (Reduction) or taking measures to keep...

Year Published: 2023Topics: Regulations & Ethical ReviewAnimal Type: All/General

Citation: Enkelmann, A., Bischoff, S. J. 2023. CIRS-LAS – a novel approach to increase transparency in laboratory animal science for improving animal welfare by reducing laboratory animal distress. Frontiers in Veterinary Science 10.