Biological Sampling & Physiological Measurement

Social housing of non-rodents during cardiovascular recordings in safety pharmacology and toxicology studies

Introduction: The Safety Pharmacology Society (SPS) and National Centre for the Replacement, Refinement & Reduction of Animals in Research (NC3Rs) conducted a survey and workshop in 2015 to define current industry practices relating to housing of non-rodents during telemetry recordings...

Year Published: 2016Topics: Biological Sampling & Physiological Measurement, External Bodily Equipment, Social Housing & CompanionshipAnimal Type: Dog, Macaque, Nonhuman Primate, Pig

Citation: Prior, H., Bottomly, A., Champéroux, P. et al. 2016. Social housing of non-rodents during cardiovascular recordings in safety pharmacology and toxicology studies. Journal of Pharmacological and Toxicological Methods 81, 75-87.

Facial thermography is not useful in assessing body temperature in common squirrel monkeys (Saimiri sciureus) in comparison to rectal temperatures

A group of 39 captive common squirrel monkeys (Saimiri sciureus) had their body temperature measurements compared by rectal thermometry and facial infrared thermal imaging (Flir i3, Flir Systems Inc). Squirrel monkeys were caught up and manually restrained for examination and...

Year Published: 2015Topics: Biological Sampling & Physiological Measurement, Welfare AssessmentAnimal Type: Nonhuman Primate, Squirrel Monkey

Citation: Pizzi, R., Dowling, A., Brown, D. et al. 2015. Facial thermography is not useful in assessing body temperature in common squirrel monkeys (Saimiri sciureus) in comparison to rectal temperatures. Journal of Zoo and Aquarium Research 3(3), 94-98.

Assessment of a noninvasive chronic glucose monitoring system in euglycemic and diabetic swine (Sus scrofa)

Models of type-I diabetes are well-characterized and commonly used in the preclinical evaluation of drugs and medical devices. The diabetic minipig is an excellent example of a translational model. However, chronic glucose monitoring in this species can be challenging; frequent...

Year Published: 2020Topics: Biological Sampling & Physiological Measurement, Disease/Experimental Model, External Bodily EquipmentAnimal Type: Pig

Citation: Ober, R. A., Geist, G. E. 2020. Assessment of a noninvasive chronic glucose monitoring system in euglycemic and diabetic swine (Sus scrofa). JAALAS 59(4), 430-437.

Analysis of hair cortisol as an indicator of chronic stress in pigs in two different farrowing systems

Confinement to farrowing crates is known to prevent sows from performing natural behavior, impairing animal welfare and possibly causing chronic stress. Hair cortisol analyses are increasingly used to detect chronic stress in animals. In the present study, hair samples were...

Year Published: 2021Topics: Biological Sampling & Physiological Measurement, Welfare AssessmentAnimal Type: Pig

Citation: Wiechers, D.-H., Brunner, S., Herbrandt, S. et al. 2021. Analysis of hair cortisol as an indicator of chronic stress in pigs in two different farrowing systems. Frontiers in Veterinary Science 8, 605078.

Alternative training method using a mouse simulator in intravenous lateral tail vein procedures

The purpose of this study was to reduce or replace mouse cadavers for use in procedural training. All participants had mixed experience in various technical procedures such as oral gavage, intraperitoneal injections, etc., but none had ever carried out intravenous...

Year Published: 2020Topics: Biological Sampling & Physiological MeasurementAnimal Type: Mouse, Rodent

Citation: Abela, C. 2020. Alternative training method using a mouse simulator in intravenous lateral tail vein procedures. Animal Technology and Welfare 19(3), 249-250.

Quantification of hair corticosterone, DHEA and testosterone as a potential tool for welfare assessment in male laboratory mice

Steroids, providing information regarding several biological patterns including stress and sexual behavior, have been investigated in different matrices in laboratory mice. Data regarding hair quantification, indicative of longer timespans when compared to blood and saliva, are lacking. The aim of...

Year Published: 2020Topics: Biological Sampling & Physiological Measurement, Welfare AssessmentAnimal Type: Mouse, Rodent

Citation: Elmi, A., Galligioni, V., Govoni, N. et al. 2020. Quantification of hair corticosterone, DHEA and testosterone as a potential tool for welfare assessment in male laboratory mice. Animals 10(12), 2408.

Conscious urine sampling and quantification from indwelling catheterization of female Yucatan swine

In addition to routine diagnostic testing of urine for health status, data from urine collection is often necessary to support various nutritional, metabolic, biochemical, and physiologic studies. Collection methods can be stressful to the animal (manual restraint), may require sedation...

Year Published: 2019Topics: Biological Sampling & Physiological Measurement, Cannulation, Catheterization, & IntubationAnimal Type: Pig

Citation: Bogins, C., Beale, C. 2019. Conscious urine sampling and quantification from indwelling catheterization of female Yucatan swine. Laboratory Animal Science Professional 7(3) (September), 44-46.

Saliva sampling in dogs: How to select the most appropriate procedure for your study

Saliva sampling is an easy, noninvasive method to assess short-term physiological changes, and as such is a valuable addition to behavioral studies in dogs. Different methods for collecting saliva samples in dogs have been reported in literature, and there appears...

Year Published: 2019Topics: Biological Sampling & Physiological MeasurementAnimal Type: Dog

Citation: Lensen, C. M. M., Moons, C. P. H., Diederich, C. 2015. Saliva sampling in dogs: How to select the most appropriate procedure for your study. Journal of Veterinary Behavior 10(6), 504-512.

Minimally-invasive, microneedle-array extraction of interstitial fluid for comprehensive biomedical applications: Transcriptomics, proteomics, metabolomics, exosome research, and biomarker identification

Interstitial fluid (ISF) has recently garnered interest as a biological fluid that could be used as an alternate to blood for biomedical applications, diagnosis, and therapy. ISF extraction techniques are promising because they are less invasive and less painful than...

Year Published: 2018Topics: Biological Sampling & Physiological MeasurementAnimal Type: Rat, Rodent

Citation: Taylor, R. M., Miller, P. R., Ebrahimi, P. et al. 2018. Minimally-invasive, microneedle-array extraction of interstitial fluid for comprehensive biomedical applications: Transcriptomics, proteomics, metabolomics, exosome research, and biomarker identification. Laboratory Animals 52(5), 526–530.

Measuring cortisol, the major stress hormone in fishes

Stress in teleosts is an increasingly studied topic because of its interaction with growth, reproduction, immune system and ultimately fitness of the animal. Whether it is for evaluating welfare in aquaculture, adaptive capacities in fish ecology, or to investigate effects...

Year Published: 2019Topics: Biological Sampling & Physiological MeasurementAnimal Type: Fish, Other Fish, Salmon, Tilapia, Trout, Zebrafish

Citation: McKenzie, D. J., Sadoul, B., Geffroy, B. 2019. Measuring cortisol, the major stress hormone in fishes. Journal of Fish Biology 94(4), 540-555.