Long-term arrhythmia analysis of primates pretreated with pyridostigmine, challenged with soman, and treated with atropine and 2-PAM (1989)

Hassler, C. R., Moutvic, R. R., Hobson, D. W. et al.

Abstract

Heart rates were significantly lower on weekend, when there was minimum research activity in the facility, while they were noted to increase on weekdays. These alterations suggest that increased heart rates in the animals were closely associated with work activity patterns, with the highest heart rates observed on Thursday when the work level in the primate facility was at its peak. Entry of technical staff into the colony could be clearly identified in the heart rate and activity recordings. Heart rates well in excess of 200 BPM were recorded when humans were in close proximity.