Influence of environmental rearing history and postsurgical environmental change on the septal rage syndrome in mice (1982)

Goodlett, C. R., Engellenner, W. J., Burright, R. G. et al.

Abstract

The restricted mice were more reactive to handling than the enriched mice presurgically (60 days old), and interactions of housing conditions and surgery were found over the seven day postsurgical handling and testing period. The restricted mice given septal lesions greatly increased in reactivity postsurgically, while the intact controls declined in reactivity over the postsurgical week.