Heart rate and activity of rhesus monkeys in response to routine events (1989)

Line, S. W., Morgan, K. N., Markowitz, H. et al.

Abstract

Adult female rhesus macaques responded with a significant, protracted increase in heart rate to being placed in transfer boxes while their dirty cages were replaced with clean ones. The mean heart rate remained elevated for two hours after completion of the procedure.... These observations are important to note if one is to avoid confounding the physiological and behavioral effects of experimental manipulations with those induced by routine husbandry. ...Variations in heart rate and activity are closely associated with human activity in the room.