Fecal corticoid metabolites in aged male and female rats after husbandry-related disturbances in the colony room (2006)

Cavigelli, S. A., Guhad, F. A., Ceballos, R. M. et al.

Abstract

Over a 3-h period, 10 male and 10 female Fischer 344 rats (age, 82 wk) were exposed to a series of events that can occur in a colony housing room (keys jingling, cage lids opening, alteration of the light cycle). Fecal metabolites in these aged rats were elevated 3- to 5-fold above baseline levels approximately 20 h after exposure to the experimental events.