Effects of blood sampling, Telazol?, and ketamine on cortisol in rhesus monkeys (Macaca mulatta) (2000)

Bentson, K. L., Capitanio, J. P., Mendoza, S. P.

Abstract

Effects of blood sampling procedures and of two immobilizing agents on pituitary adrenal activity were examined in 16 armpull-trained adult male rhesus macaques. ...Subjects were restrained in their home cage, a blood sample collected via armpull.... During the morning period, cortisol values remained constant for the saline condition. .....During the afternoon period, cortisol decreased across the first 30 minutes for all agents ....The results indicate blood sampling procedures are relatively innocuous for experienced rhesus macaque males. The data also suggest ketamine and Telazol affect the pituitary-adrenal system differently.