Comparison of technicians' ability to detect clinical signs in rats housed in solid-bottomed cages with bedding versus wire-bottomed cages (2005)

Van Vleet, T. R., Rhodes, J. W., Waites, C. R. et al.

Abstract

The only difference observed was a diminished ability to detect blue urine from new methylene blue adminstation in wire-bottomed cages. Concerns about the technical staff's inability to detect clinical signs in toxicology tests should not prevent investigators from using solid-bottomed cages with bedding.