Assessment of stress in non-human primates: application of the neutrophil activation test (2005)

Honess, P. E., Marin, C., Brown, A. P. et al.

Abstract

All macaques were group-housed indoors in either a traditional caging system of three linked modules of typical reinforced stainless steel two-tier laboratory cages, or in open-rooms containing either these cages with the fronts removed or no caging at all. ... Animals housed in a traditioal caging system produced a significantly lower leukocyte response than animals housed in open-rooms, indicating that there was a higher level of stress associated with caged housing than open-room housing.