A surgical procedure and tethering system for chronic blood sampling, infusion, and temperature monitoring in caged nonhuman primates (1984)

McNamee, G. A., Wannemacher, R. W., Dinterman, R. E. et al.

Abstract

The stress of chairing the monkeys may result in a significant decrease in hemoglobin, hematocrit, and lymphocyte concentration with an accompanying neutrophilia. In addition, chair-restrained monkeys tend to develop lower leg edema and decubital ulcers on long-term studies. A tethering system is described to circumvent the problems associated with chair restraint.