Nonhuman Primate

Noninvasive genotyping of common marmoset (Callithrix jacchus) by fingernail PCR

The common marmoset (Callithrix jacchus) is a New World primate that is a useful model for medical studies. In this study, we report a convenient, reliable, and noninvasive procedure to genotype a living common marmoset by using fingernails. This method...

Year Published: 2015Topics: Identification MethodAnimal Type: Marmoset, Nonhuman Primate

Citation: Takabayashi, S., Katoh, H. 2015. Noninvasive genotyping of common marmoset (Callithrix jacchus) by fingernail PCR. Primates 56(3), 235-240.

Behavioural and physiological effects of housing type on laboratory housed female rhesus macaques (Macaca mulatta)

Due to the despotic nature of rhesus macaques (Macaca mulatta) and their frequent use in biomedical research, it is important to understand the impact that standard housing practices can have on individuals of this species in order to improve practices...

Year Published: 2015Topics: Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Cassidy, L., Semple, S., Hannibal, D. et al. 2015. Behavioural and physiological effects of housing type on laboratory housed female rhesus macaques (Macaca mulatta). Folia Primatologica 86(4), 259-60.

Training pair-housed Rhesus macaques (Macaca mulatta) using a combination of negative and positive reinforcement

When training animals, time is sometimes a limiting factor hampering the use of positive reinforcement training (PRT) exclusively. The aim of this study was to evaluate the effects of a combination of negative and positive reinforcement training (NPRT). Twenty nave...

Year Published: 2015Topics: Animal TrainingAnimal Type: Macaque, Nonhuman Primate

Citation: Wergrd, E., Temrin, H., Forkman, B. et al. 2015. Training pair-housed Rhesus macaques (Macaca mulatta) using a combination of negative and positive reinforcement. Behavioural Processes 113, 51-59.

Positive reinforcement training: a tool for care and management of captive vervet monkeys (Chlorocebus aethiops)

In modern zoos, training should be an integral component of the animal care and management. The benefits of training include the opportunity for positive interactions with caretakers. This study was carried out with a group of vervet monkeys (Chlorocebus aethiops)...

Year Published: 2015Topics: Animal TrainingAnimal Type: Nonhuman Primate, Vervet (African Green Monkey)

Citation: Spiezio, C., Piva, F., Regaiolli, B. et al. 2015. Positive reinforcement training: a tool for care and management of captive vervet monkeys (Chlorocebus aethiops). Animal Welfare 24, 283-290.

Positive reinforcement methods to train chimpanzees to cooperate with urine collection

Positive reinforcement training can be used in many ways to enhance the welfare of captive primates. Training for biologic sample collection is one application of positive reinforcement training. In this study, 35 adult female chimpanzees were trained to cooperate with...

Year Published: 2015Topics: Animal Training, Biological Sampling & Physiological MeasurementAnimal Type: Chimpanzee, Nonhuman Primate

Citation: Bloomsmith, M., Kim, N., Franklin, A. et al. 2015. Positive reinforcement methods to train chimpanzees to cooperate with urine collection. JAALAS 54, 66-69.

Crowding increases salivary cortisol but not self-directed behavior in captive baboons

Reduced space can lead to crowding in social animals. Crowding increases the risk of agonistic interactions that, in turn, may require additional physiological defensive coping mechanisms affecting health. To determine the stress induced from increased social density in a group...

Year Published: 2015Topics: Abnormal/Problematic Behavior, Emotion, Pain, & Sentience, Stocking DensityAnimal Type: Baboon, Nonhuman Primate

Citation: Pearson, B. L., Reeder, D. M., Judge, P. G. 2015. Crowding increases salivary cortisol but not self-directed behavior in captive baboons. American Journal of Primatology 77, 462-67.

Effects of group housing on ECG assessment in conscious cynomolgus monkeys

Assessing the cardiovascular safety of new chemical or biological entities is important during pre-clinical development. Electrocardiogram (ECG) assessments in non-human primate (NHP) toxicology studies are often made using non-invasive telemetry systems. We investigated whether ECG recording was feasible during group...

Year Published: 2015Topics: Biological Sampling & Physiological Measurement, External Bodily Equipment, Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Xing, G., Lu, J., Hu, M. et al. 2015. Effects of group housing on ECG assessment in conscious cynomolgus monkeys. Journal of Pharmacological and Toxicological Methods 75, 44-51.

Miniaturized blood sampling techniques to benefit reduction in mice and refinement in nonhuman primates: Application to bioanalysis in toxicity studies with antibody-drug conjugates

Minimizing the number of animals in regulatory toxicity studies while achieving study objectives to support the development of future medicines contributes to good scientific and ethical practices. Recent advances in technology have enabled the development of miniaturized blood sampling methods...

Year Published: 2015Topics: Biological Sampling & Physiological MeasurementAnimal Type: Baboon, Capuchin, Chimpanzee, Lemur, Macaque, Marmoset, Mouse, Nonhuman Primate, Other Nonhuman Primate, Owl Monkey, Rodent, Squirrel Monkey, Vervet (African Green Monkey)

Citation: Caron, A., Lelong, C., Pascual, M. H. et al. 2015. Miniaturized blood sampling techniques to benefit reduction in mice and refinement in nonhuman primates: Application to bioanalysis in toxicity studies with antibody-drug conjugates. JAALAS 54(2), 145-152.

Advantages and risks of housing changes to improve animal wellbeing in a breeding colony of common marmosets (Callithrix jacchus)

Between 1975 and 2014, housing conditions for laboratory-housed marmosets changed dramatically after the introduction of new guidelines designed to improve their care and wellbeing. According to these guidelines, our facility provided marmosets with outside enclosures, switched to deep litter as...

Year Published: 2015Topics: Environmental Enrichment, Housing, Husbandry & Management, Welfare AssessmentAnimal Type: Marmoset, Nonhuman Primate

Citation: Bakker, J., Ouwerling, B., Hedit, P. J. et al. 2015. Advantages and risks of housing changes to improve animal wellbeing in a breeding colony of common marmosets (Callithrix jacchus). JAALAS 54(3), 273-279.

Non-invasive blood pressure measurement: values, problems and applicability in the common marmoset (Callithrix jacchus)

The common marmoset (Callithrix jacchus, C. j.) is an established primate model in biomedical research and for human-related diseases. Monitoring of cardiovascular parameters including blood pressure (BP) is important for the health surveillance of these experimental animals and the quantification...

Year Published: 2015Topics: Biological Sampling & Physiological MeasurementAnimal Type: Marmoset, Nonhuman Primate

Citation: Mietsch, M., Einspanier, A. 2015. Non-invasive blood pressure measurement: values, problems and applicability in the common marmoset (Callithrix jacchus). Laboratory Animals 49(3), 241-250.