Mouse

Behavioral assessment of intermittent wheel running and individual housing in mice in the laboratory

It can be concluded that both socially and physically enriched environments do not influence wheel running frequency patterns.

Year Published: 2005Animal Type: Mouse, Rodent

Citation: Pham, T. M., Brene, S., Baumans, V. 2005. Behavioral assessment of intermittent wheel running and individual housing in mice in the laboratory. Journal of Applied Animal Welfare Science 8, 157-173.

Breeding colony housing: A comparison of two cages sized

Based on our findings we determined that large boxes [8 x 17 in. versus small 6 x 10 in. standard boxes] improved breeding performance [of breeding C57BL/6 mice], required less labor, and provided a better microenvironment.

Year Published: 2005Animal Type: Mouse, Rodent

Citation: McMahon, K., Haist, C., Dysko, R. 2005. Breeding colony housing: A comparison of two cages sized. American Association for Laboratory Animal Science [AALAS] Meeting Official Program, 127(Abstract).

Collecting blood from rodents: A discussion by the Laboratory Animal Refinement and Enrichment Forum

The question was asked: "In your own experience, what is the least disturbing technique - from the subject's point of view! - of blood collection for rodents?" In summary, it is fair to conclude the clinical and ethical concerns outweigh...

Year Published: 2005Topics: Biological Sampling & Physiological MeasurementAnimal Type: Chinchilla, Gerbil, Guinea Pig, Hamster, Mouse, Other Rodent, Rat, Rodent

Citation: Luzzi, M., Skoumbourdis, E., Baumans, V. et al. 2005. Collecting blood from rodents: A discussion by the Laboratory Animal Refinement and Enrichment Forum. Animal Technology and Welfare 4, 99-102.

Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice

Cerebral deposition of beta-amyloid (Abeta) peptides is an invariant pathological hallmark in brains of patients with Alzheimer's disease (AD) and transgenic mice coexpressing familial AD-linked APP and PS1 variants. We now report that exposure of transgenic mice to an enriched...

Year Published: 2005Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Lazarov, O., Robinson, J., Tang, Y. P. et al. 2005. Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice. Cell 120, 701-713.

Environmental enrichment for laboratory rodents

In this article, laws and guidelines relating to rodent enrichment are reviewed, the natural behaviors of select rodent species are discussed, and an overview of widely used types of enrichment in laboratory rodent management is provided. Survey data on current...

Year Published: 2005Topics: Environmental Enrichment, Natural Behavior, Regulations & Ethical ReviewAnimal Type: Guinea Pig, Hamster, Mouse, Rat, Rodent

Citation: Hutchinson, E., Avery, A., Van de Woude, S. 2005. Environmental enrichment for laboratory rodents. ILAR Journal 46(2), 148-161.

Using obese mouse models in research: Special considerations for IACUC members, animal care technicians, and researchers

General discussion of husbandry issues specifically related to obese mice.

Year Published: 2005Animal Type: Mouse, Rodent

Citation: Good, D. J. 2005. Using obese mouse models in research: Special considerations for IACUC members, animal care technicians, and researchers. Lab Animal 34(2), 30-37.

A rapid, simple, and humane method for submandibular bleeding of mice using a lancet

Methods for obtaining blood samples frommicetend to be difficult, inhumane, or both. The authors describe an inexpensive, disposable, single-use lancet for submandibular bleeding ofmicethat allows investigators to quickly draw 0.2-0.5 ml of blood without the use of anesthesia.

Year Published: 2005Animal Type: Mouse, Rodent

Citation: Golde, W. T., Gollobin, P., Rodriguez, L. L. 2005. A rapid, simple, and humane method for submandibular bleeding of mice using a lancet. Lab Animal 34(9), 39-43.

Pair housing affects anxiety-like behaviors induced by a social but not by a physiological stressor in male Swiss mice

Pair housing proved to be effective in modulating anxiety-like behaviour.

Year Published: 2005Animal Type: Mouse, Rodent

Citation: Gasparotto, O. C., Lopes, D. M., Carobrez, S. G. 2005. Pair housing affects anxiety-like behaviors induced by a social but not by a physiological stressor in male Swiss mice. Physiology and Behavior 85(5), 603-612.

Rx for mice: Take enrichment and call me in the morning

In a first phase, the effectiveness of several enrichment devices was evaluated: flavored nylon chew bones, colored tunnels, igloo shaped houses, and a life-sized rubber mouse. Mice, whether alone or in a group, had constant interaction with the houses.... I...

Year Published: 2005Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Gaskin, N. 2005. Rx for mice: Take enrichment and call me in the morning. Tech Talk [The Newsletter for Laboratory Animal Science Technicians] 10(6).

Effect of two types of environmental enrichment for singly housed mice on food intake and weight gain

Adult mice showed no change in either food intake or weight gain when an Igloo refuge was introduced into their cage.

Year Published: 2005Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Robertson, K. L., Rowland, N. E. 2005. Effect of two types of environmental enrichment for singly housed mice on food intake and weight gain. Lab Animal 34(9), 29-32.