Macaque

Higher levels of submissive behaviors at the onset of the pairing process of rhesus macaques (Macaca mulatta) are associated with lower risk of wounding following introduction

Social housing of rhesus macaques (Macaca mulatta) is considered to be the cornerstone of behavioral management programs in biomedical facilities. However, it also involves the risk of socially inflicted trauma. The ability to avoid such trauma would contribute to the...

Year Published: 2017Topics: Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Pomerantz, O., Baker, K. C. 2017. Higher levels of submissive behaviors at the onset of the pairing process of rhesus macaques (Macaca mulatta) are associated with lower risk of wounding following introduction. American Journal of Primatology 79(8), e22671.

Effects of human management events on conspecific aggression in captive rhesus macaques (Macaca mulatta)

Conspecific aggression in outdoor-housed rhesus macaques (Macaca mulatta) at primate research facilities is a leading source of trauma and can potentially influence animal wellbeing and research quality. Although aggression between macaques is a normal part of daily social interactions, human...

Year Published: 2017Topics: Husbandry & Management, Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Theil, J. H., Beisner, B. A., Hill, A. E. et al. 2017. Effects of human management events on conspecific aggression in captive rhesus macaques (Macaca mulatta). JAALAS 56(2), 122-130.

Comparison of saliva collection methods for the determination of salivary cortisol levels in rhesus macaques (Macaca mulatta), cynomolgus macaques (Macaca fascicularis), and African green monkeys (Chlorocebus aethiops)

The ability to quickly and accurately determine cortisol as a biomarker for stress is a valuable tool in assessing the wellbeing of NHP. In this study, 2 methods of collecting saliva (a commercial collection device and passive drool) and the...

Year Published: 2017Topics: Biological Sampling & Physiological MeasurementAnimal Type: Macaque, Nonhuman Primate, Vervet (African Green Monkey)

Citation: Rapp-Santos, K. J., Altamura, L. A., Norris, S. L. et al. 2017. Comparison of saliva collection methods for the determination of salivary cortisol levels in rhesus macaques (Macaca mulatta), cynomolgus macaques (Macaca fascicularis), and African green monkeys (Chlorocebus aethiops). JAALAS 56(2), 181-189.

Using a cageside device for testing glycosylated hemoglobin in cynomolgus macaques (Macaca fascicularis)

Recording an accurate body temperature is important to assess an animal's health status. We compared temperature data from sedated cynomolgus macaques (Macaca fascicularis) to evaluate differences between rectal, infrared (inguinal and chest), and implanted telemetry techniques with the objective of...

Year Published: 2017Topics: Biological Sampling & Physiological MeasurementAnimal Type: Macaque, Nonhuman Primate

Citation: Johnston, J. M., Wilson, J. M., Smith, A. L. et al. 2017. Using a cageside device for testing glycosylated hemoglobin in cynomolgus macaques (Macaca fascicularis). JAALAS 56(1), 90-94.

Pharmacokinetics of a novel, transdermal fentanyl solution in rhesus macaques (Macaca mulatta)

Rhesus macaques (Macaca mulatta) are the most commonly used NHP biomedical model and experience both research and clinical procedures requiring analgesia. Opioids are a mainstay of analgesic therapy. A novel, transdermal fentanyl solution (TFS) has been developed as a long-acting,...

Year Published: 2017Topics: AnalgesiaAnimal Type: Macaque, Nonhuman Primate

Citation: Salyards, G. W., Lemoy, M.-J., Knych, H. K. et al. 2017. Pharmacokinetics of a novel, transdermal fentanyl solution in rhesus macaques (Macaca mulatta). JAALAS 56(4), 443-451.

Physiologic correlates of interactions between adult male and immature long-tailed macaques (Macaca fascicularis)

Interactions between adult males and immature members of the same species are rare in most mammals; in contrast, an estimated 40% of primate species are characterized by an involvement of males in the social life of infants and juveniles. The...

Year Published: 2017Topics: Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Bardi, M., Prugh, A. M., Eubanks, B. T. et al. 2017. Physiologic correlates of interactions between adult male and immature long-tailed macaques (Macaca fascicularis). JAALAS 56(6), 718-728.

Two methods of social separation for paired adolescent male rhesus macaques (Macaca mulatta)

Literature-based recommendations regarding how to separate pairs of laboratory-housed NHP when required for research, veterinary, or management needs are unavailable. This study assessed 2 separation techniques—rapid and stepwise—to determine whether a period of limited social access mitigates the behavioral stress...

Year Published: 2017Topics: Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Truelove, M. A., Martin, A. L., Perlman, J. E. et al. 2017. Two methods of social separation for paired adolescent male rhesus macaques (Macaca mulatta). JAALAS 56(6), 729-734.

Evaluation of a zinc gluconate neutralized with arginine product as a nonsurgical method for sterilization of rhesus macaques (Macaca mulatta)

Because rhesus macaques (Macaca mulatta) are prolific breeders, overpopulation can be problematic in both research and feral populations. Currently, the most effective contraceptive methods are hormonal control in female macaques and vasectomies in males. These methods each come with innate...

Year Published: 2017Topics: ReproductionAnimal Type: Macaque, Nonhuman Primate

Citation: Woodward, K. N., Keesler, R. I., Reader, J. R. et al. 2017. Evaluation of a zinc gluconate neutralized with arginine product as a nonsurgical method for sterilization of rhesus macaques (Macaca mulatta). JAALAS 56(5), 520-526.

Comparison of direct and indirect methods of measuring arterial blood pressure in healthy male rhesus macaques (Macaca mulatta)

Blood pressure is a critical parameter for evaluating cardiovascular health, assessing effects of drugs and procedures, monitoring physiologic status during anesthesia, and making clinical decisions. The placement of an arterial catheter is the most direct and accurate method for measuring...

Year Published: 2018Topics: Biological Sampling & Physiological MeasurementAnimal Type: Macaque, Nonhuman Primate

Citation: France, L. K., Vermillion, M. S., Garrett, C. M. 2018. Comparison of direct and indirect methods of measuring arterial blood pressure in healthy male rhesus macaques (Macaca mulatta). JAALAS 57(1), 64-69.

Effect of chronic social stress on prenatal transfer of antitetanus immunity in captive breeding rhesus macaques (Macaca mulatta)

Because tetanus can cause significant morbidity and mortality in NHP, colonywide vaccination with tetanus toxoid is recommended for outdoor breeding colonies of rhesus macaques, with primary immunizations commonly given to infants at 6 mo of age followed by booster vaccines...

Year Published: 2018Topics: Reproduction, Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Stammen, R. L., Cohen, J. K., Meeker, T. L. et al. 2018. Effect of chronic social stress on prenatal transfer of antitetanus immunity in captive breeding rhesus macaques (Macaca mulatta). JAALAS 57(4), 357-367.