All/General

Why every scientist should care about animal welfare: Abnormal repetitive behavior and brain function in captive animals

Barren laboratory housing also induces abnormal behaviors in many species, particularly stereotypies, fur and feather plucking, and self-mutilation. Similar behaviors in human mental disorder are correlated with dysfunction in brain areas that control the selection and sequencing of behavior. Experiments...

Year Published: 2002Topics: Abnormal/Problematic BehaviorAnimal Type: All/General, Mouse, Rodent

Citation: Garner, J. P. 2002. Why every scientist should care about animal welfare: Abnormal repetitive behavior and brain function in captive animals. Proceedings of the World Congress on Alternatives and Animal Use in the Life Sciences, 95 (Abstract).

Guidelines for the design and statistical analysis of experiments using laboratory animals

If scientists are to have the privilege of being allowed to do painful experiments on animals, they must ensure that their experiments are beyond criticism.

Year Published: 2002Topics: Regulations & Ethical ReviewAnimal Type: All/General

Citation: Festing, M. F. W., Altman, D. G. 2002. Guidelines for the design and statistical analysis of experiments using laboratory animals. ILAR Journal 43(4), 244-258.

Prediction and preparation: Pavlovian implications of research animals discriminating among humans

The presence of humans as possible confounding variables is discussed. Human subjects are rarely if ever passive sources of data in studies involving animals.

Year Published: 2002Topics: Human-Animal InteractionAnimal Type: All/General

Citation: Davis, H. 2002. Prediction and preparation: Pavlovian implications of research animals discriminating among humans. ILAR Journal 43(1), 19-26.

Reducing the invasiveness of obtaining blood-born measures in animals

An often-found confounding problem is that the experimental techniques may themselves elicit stress responses in the animal. In particular, many changes of interest are reflected in analytes in the blood. Collection of blood is often stressful and mildly noxious. .....

Year Published: 2002Animal Type: All/General

Citation: Cook, C. 2002. Reducing the invasiveness of obtaining blood-born measures in animals. Proceedings of the World Congress on Alternatives and Animal Use in the Life Sciences, 108 (Abstract).

The International Symposium on Regulatory Testing and Animal Welfare: Recommendations on best scientific practices for animal care and regulatory toxicology

The key conclusion from the group's initial discussions was that enough information was now available to make robust recommendations for animal care best practices. Implementation, not information, is therefore the critical issue [p.123]... Well-implemented enrichment may reduce variability rather than...

Year Published: 2002Topics: Environmental EnrichmentAnimal Type: All/General

Citation: Morris, T., Goulet, S., Morton, D. 2002. The International Symposium on Regulatory Testing and Animal Welfare: Recommendations on best scientific practices for animal care and regulatory toxicology. ILAR Journal 43(Supplement), S123-S125.

Definition of Pain and Distress and Reporting Requirements for Laboratory Animals: Proceedings

Year Published: 2002Animal Type: All/General

Citation: Institute for Laboratory Animal Research 2002. Definition of Pain and Distress and Reporting Requirements for Laboratory Animals: Proceedings . National Academy Press, Washington, DC.

An additional R – Remembering the animals

The need to recognize the existence of bonds between caregivers and their animals is discussed. Involvement in a venue to acknowledge the contributions animals make to teaching, testing, and research can be a satisfying and meaningful experience.

Year Published: 2002Topics: Human-Animal InteractionAnimal Type: All/General

Citation: Iliff, S. A. 2002. An additional R - Remembering the animals. ILAR Journal 43(1), 38-47.

Developing a close bond with research animals

Developing a close bond with research animals can only be a good thing. I have seen the results of both and was very disturbed when people seemed to regard the animals only as test subjects and not as living beings....

Year Published: 2002Topics: Human-Animal InteractionAnimal Type: All/General

Citation: Hunnicutt, T. 2002. Developing a close bond with research animals. Laboratory Animal Refinement and Enrichment Forum (electronic discussion group), October 29, 2002.

Animal use in the United Kingdom

Approximately 2.6 million animals are currently used each year - 85% of which are rodents or birds, with cats, dogs, equidae, and non-human primates accounting for less then 1% of the animals used.

Year Published: 2002Animal Type: All/General

Citation: Richmond, J. 2002. Animal use in the United Kingdom. Proceedings of the World Congress on Alternatives and Animal Use in the Life Sciences, 126 (Abstract).

Refinement, reduction, and replacement of animal use for regulatory testing: Future improvements and implementation within the regulatory framework

Many are critical of how regulatory testing practices have evolved and become established—critical both of the scientific rational and the animal welfare costs. The test of whether we are more enlightened than our predecessors will be whether, armed with more...

Year Published: 2002Topics: Regulations & Ethical ReviewAnimal Type: All/General

Citation: Richmond, J. 2002. Refinement, reduction, and replacement of animal use for regulatory testing: Future improvements and implementation within the regulatory framework. ILAR Journal 43(Supplement), S63-S68.